Aquaticpollutants

PAIRWISE aims to advance knowledge of antimicrobial resistance as a pollution in aquatic environments, wildlife, and livestock. PAIRWISE focuses on dispersal and dynamics of antibiotic resistant bacteria, antibiotic resistance genes and antibiotics in aquatic environments affected by wastewater treatment plants (WWTPs). Overall goals are to understand: i) dispersal of antibiotic resistant bacteria, antibiotic resistance genes and antibiotics in surface waters downstream of WWTPs, ii) carriage of antibiotic resistant bacteria and antibiotic resistance genes in livestock linked to surface waters influenced by WWTPs, iii) role of aquatic birds in dispersal of antibiotic resistant bacteria and antibiotic resistance genes. Issues from the JPI call tackled by PAIRWISE include, but are not limited to: entry points and fate of antibiotic resistant bacteria, antibiotic resistance genes and antibiotics; identification of antibiotic resistance genes and antibiotic resistant bacteria useful as indicators; providing insight to fate and transport of antibiotic resistant bacteria, antibiotic resistance genes and antibiotics to, within, and from aquatic ecosystems, and the role of aquatic birds in such events.

PAIRWISE will assess the influence of antimicrobial resistance in agricultural settings and improve understanding of the dissemination and sustainment of antimicrobial resistance in the interface between humans, wildlife, and livestock with a One Health perspective. It will provide vital knowledge for policy makers and end-users, facilitating informed decisions on

mitigation strategies.The consortium consists of 7 partners from 5 countries and 2 continents forming an multidisciplinary team.